Q&A: How to Safely Handle Your Antibody Drug Conjugate

Antibody–drug conjugates are highly potent biological drugs used to treat cancer patients. They are made up of three parts: an antibody, a linker, and a payload. Because they directly convey highly potent anticancer payloads into the tumor, they can be considered the Trojan horses of the medicine world.

Manufacturing ADCs is challenging because of their strict requirements for containment. If a growing business has internal expertise in the necessary specialized occupational toxicology and industrial hygiene, it will be in a good place to ensure their ADCs are handled safely. In a recent webinar hosted by Lonza, How to Safely Handle Your Antibody Drug Conjugate, experts from the multinational CDMO explored the key factors involved in ensuring the safe handling of ADCs. These include toxicological and risk assessments, best practices for containment, and occupational hygiene monitoring.

A Q&A session was held following the webinar. This allowed attendees to gain a better understanding of how Lonza approaches the safe handling of these drugs.