Purification Of Antibodies With Nuvia™ wPrime 2A Media, A Scalable Hydrophobic Weak Anion Exchange Resin

Efficient mAb polishing requires balancing impurity clearance with product recovery. Learn how a DoE-guided approach was used to optimize Nuvia™ wPrime 2A Media for aggregate removal in flow-through mode, reducing high molecular weight species from 7.3% to 0.7% with 85% mAb monomer recovery. Download the application note to review the experimental approach and column validation data.