Process Control And Performance: Allegro™ Connect Depth Filtration System

By Nigel Jackson, Principal R&D Engineer

The Allegro Connect Depth Filtration System is a single-use automated filtration system designed to deliver robust process control during the clarification/harvest step.

This next-generation compact and elegant system is designed to minimize risk through a fully automated process with recipe-controlled steps, including pre-use manifold leak test, system priming, product filtration, and buffer chase with all data stored in a batch reporting system, significantly reducing non-conformities and manual labor.

New design features allow configurability of each manifold to meet various process needs, supporting different process trending sensors and a wide range of liquid filter capsules, whilst also accommodating non-Cytiva filters.

Explore a demonstration of strategic process control in terms of flow and pressure, by utilizing the Allegro Connect Depth Filtration System, for effective depth filter processing. Learn about the effective product recovery (100%) of IgG solution, including recovery of excess product that is held up within the filters during processing.