Product/Service

Praesto® Jetted A50 - Protein And MAb Purification

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Praesto Jetted A50 is a high-performance agarose-based protein A resin that delivers exceptional performance in terms of capacity, pressure flow, and lifetime. Purolite is the only manufacturer of uniform particle size agarose resins.

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Principal Applications

  • Protein purification (20-500 kDa)
  • MAb Purification

Advantages

  • Manufactured using patented Jetting technique
  • Uniform particle size
  • Repligen® NGL-ImpactTM A ligand
  • Highest dynamic binding capacity (~80g/l)
  • Exceptional alkaline stability
  • Enhanced pressure/flow performance
  • Manufactured with reduced environmental impact

Regulatory Approvals

  • Manufactured under GMP conditions

Typical Packaging

  • Bulk Resin
  • Production-Scale OPUS® Columns
  • OPUS® Robocolumns®
  • OPUS® MiniChrom Columns
  • HT Columns

Typical Physical & Chemical Characteristics:

Polymer Structure Highly cross linked agarose
Appearance Spherical, uniform size beads supplied in 20% ethanol slurry. On request 2% benzylalcohol
Functional Group Protein A
Dynamic binding capacity Up to 70 mg mAb/ml resin
  Up to 80 mg hIgG/ml resin
  (10 minute residence time)
Average Particle Size 50 µm
Particle size range (micron) >95% between 35-90 µm
Pressure/Flow specifications Up to 200 cm/h (30 x 20 cm)
pH stability, working range 3 - 12
pH stability, CIP (short term) 3 - 14
Recommended Storage 2- 8°C in 20% ethanol

Purolite, An Ecolab Company