Praesto™ Jetted A50 HipH Chromatography Resin

Purification challenges for acid-sensitive therapeutic molecules, such as Fc-based IgGs, often lead to reduced yields and increased aggregation due to instability at low pH levels. Purolite™'s Praesto™ Jetted A50 HipH enables high-performance elution of these molecules at higher pH levels, minimizing aggregation and enhancing recovery. Built with patented Jetting technology, this resin features uniform 50 µm beads, high dynamic binding capacity, and alkaline stability, ensuring consistent results while promoting sustainability through reduced solvent and water usage.

With the ability to elute monoclonal antibodies at pH levels up to 5, Praesto™ Jetted A50 HipH streamlines workflows, alleviates downstream polishing burdens, and accelerates time to market. Designed for advanced purification needs, this innovative resin is ideal for tackling today’s complex biopharmaceutical challenges with efficiency and reliability.