News | May 11, 2011

Powerful Bioreactor And Perfusion Application For Biotech Users Provided By PBS Biotech® And Refine Technology

Source: Refine Technology, LLC

Bench-top size, plug and play bioreactor in tandem with the low profile and high performance ATF™ System on display at ESACT in Vienna

Refine Technology, LLC, a manufacturer of novel filtration systems used in the fast growing biotechnology market, announced recently it has partnered with PBS Biotech, Inc., a developer of state of the art single-use bioreactors, to provide a powerful perfusion application providing high cell density solutions for biotech customers. The PBS 15 liter single-use bioreactor and the Refine Technology ATF4 system will be on display at the ESACT conference May 15-18 in Vienna.

PBS Biotech™ and Refine Technology, two technology leaders in cell culture development, are the ideal pair for biotech lab to production perfusion applications. Boasting low profile, high performance and easy to use systems, the PBS Biotech 15L and PBS 80L single-use bioreactors can be configured with the Refine Technology ATF4 System and ATF6 System, respectively.

PBS bioreactors feature low shear mixing and high mass transfer rates from the patented Air Wheel™ mixing mechanism, making them a perfect complement to the Refine Technology ATF™ System which provides a reliable and efficient process of cell separation and supports cell growth to extreme concentrations. The ATF System allows increased volumetric productivity and reduced bioreactor size. Together the PBS Biotech single-use bioreactors and the Refine Technology perfusion systems are ideal for demanding R&D laboratory to clinical stage high-density cell culture applications including:

  • Concentrated perfusion
  • Concentrated fed batch
  • Continuous culture
  • Primary recovery/clarification

Key Benefits of the PBS/Refine Technology Solution:

  • Significantly increased cell density
  • Simpler cell separation
  • Low profile, ease of use and high performance
  • Reduced equipment costs
  • Reduce vaccine and protein development and production costs
  • Increase operational flexibility and process efficiency

About Refine Technology
Refine Technology was founded in 1999 with a vision to bring to the biopharmaceutical market cell separation systems that allow for increased productivity of cell derived biopharmaceuticals. Refine soon introduced its patented ATF System which is now being used in the development and manufacturing facilities of many biological and pharmaceutical companies.

About PBS Biotech
PBS Biotech, Inc. is a US corporation that manufactures fully scalable and easy to use single-use bioreactors for global biotechnology organizations. The company has patented innovative industrial designs and advanced software driven control systems that produce low shear, cell culture solutions improving operational flexibility and process efficiency, reducing operating costs and accelerating time to market for biotechnology customers. With headquarters in Camarillo, CA. the company is poised for rapid growth to support industry demand for single-use technologies.

SOURCE: Refine Technology, LLC