Polyclonal (Rabbit) Anti-LXR Antibody
Source: ABR—Affinity BioReagents
Liver X receptors, LXRs, are oxysterol activated nuclear receptors which are involved in the regulation of genesis and metabolism of cholesterols and bile acids
Liver X receptors, LXRs, are oxysterol activated nuclear receptors which are involved in the regulation of genesis and metabolism of cholesterols and bile acids. LXRs for heterodimer complexes with the retinoic acid receptors once activated by their respective oxysterol ligands. Two known isoforms, alpha and beta, are differentially expressed; the alpha isoform predominantly expressed in liver, whereas beta isoform expression has been shown to be ubiquitous.
In Western blots of full-length human recombinant LXR alpha, PA1-331 detects a band of ~64 kDa representing the LXR alpha protein. PA1-331 does not cross-react with human recombinant LXR beta protein.
PA1-331 immunizing peptide corresponds to amino acids 318-329 of the human LXR alpha protein. This sequence is completely conserved between human and mouse.
ABR—Affinity BioReagents, 14818 West 6th Avenue, Suite 10A, Golden, CO 80401. Tel: 303-278-4535; Fax: 303-278-2424.
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