Product/Service

Polyclonal (Rabbit) Anti-LXR Alpha Antibody

Source: ABR—Affinity BioReagents
Liver X receptors, LXRs, are oxysterol activated nuclear receptors which are involved in the regulation of genesis and metabolism of cholesterols and bile acids
Liver X receptors, LXRs, are oxysterol activated nuclear receptors which are involved in the regulation of genesis and metabolism of cholesterols and bile acids. LXRs for heterodimer complexes with the retinoic acid receptors once activated by their respective oxysterol ligands. Two known isoforms, alpha and beta, are differentially expressed; the alpha isoform predominantly expressed in liver, whereas beta isoform expression has been shown to be ubiquitous.

PA1-330 detects liver X receptor (LXR) alpha recombinant human protein. This antibody does not cross-react with human recombinant LXR beta protein. PA1-330 has been successfully used in Western blot procedures. By Western blot this antibody detects an ~64 kDa protein representing the LXR alpha recombinant protein.

PA1-330 immunizing peptide corresponds to amino acids 318-329 of the human LXR alpha protein. This peptide (Cat. # PEP-114) is available for use in neutralizatin and control experiments.

ABR—Affinity BioReagents, 14818 West 6th Avenue, Suite 10A, Golden, CO 80401. Tel: 303-278-4535; Fax: 303-278-2424.