Plasmid DNA
Source: AGC Biologics
AGC Biologics has been manufacturing plasmid DNA (pDNA) for over 10 years. We are experienced in both clinical and commercial pDNA manufacturing. AGC Biologics has expanded its capabilities by extending services in hosts and plasmids (low and high copy pDNA expression systems) via a robust toolbox in process development with scales of 1L to 10L. These processes can easily be scaled up to 1000L GMP manufacturing.
pDNA can been used for diverse applications:
- DNA adjuvants and vaccines
- RNA drugs and vaccines
- Cell-free protein expression platforms
- Viral vector manufacturing, including for:
- Lentivirus
- Adeno-associated virus (AAV)-based therapeutics
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