Peptide Mapping Study On Human Erythropoietin (EPO): A Complex N- and O-Linked Glycoprotein

By Sibylle Heidelberger, Xuezhi Bi, Zhengwei Chen, Zoe Zhang, and Kerstin Pohl

Streamlined N- and O-linked glycopeptide characterization using the ZenoTOF 7600 system with the new Biologics Explorer software from SCIEX .

A newly integrated and easy-to-use peptide mapping workflow for the analysis of standard monoclonal antibodies (mAbs) is providing organizations with a streamlined workflow for the analysis of both collision induced dissociation (CID) and electron activated dissociation (EAD) data. The new Biologics Explorer software from SCIEX includes Genedata algorithms for data processing, reviewing and final reporting. Read the details on peptide mapping analysis of erythropoietin (EPO) with a specific focus on complex N- and O-linked glycans using the prebuilt peptide mapping workflow in Biologics Explorer software. This study highlights key features for facilitating peptide mapping with CID and EAD.