Pellicon® Single-Pass Tangential Flow Filtration

Pellicon® single-pass tangential flow filtration (single-pass TFF) is a versatile technology for more productive, high capacity and cost effective downstream processes that allows facilities to meet the demands of higher titer and connected or continuous processes. Its small footprint makes single-pass TFF convenient to implement anywhere in a process where volume reduction is needed to eliminate tank bottlenecks, reduce column sizes, and/or increase the performance of chromatography and filtration steps.

As part of the BioContinuum™ Ultrafiltration Platform, Pellicon® single-pass TFF is a powerful purification tool that runs at constant operating conditions to concentrate product pools without recirculation, allowing for higher final concentrations and higher product recovery compared to traditional batch processes. It can easily run connected with other steps to reduce in-process volumes and intensify operations in the purification of therapeutic proteins.