pDNA Manufacturing

Plasmid DNA manufacturing services offer a comprehensive, flexible platform designed to support projects ranging from basic research to clinical development. The workflow includes optional strain development, GMP and non‑GMP cell banking, process optimization for yield and purity, scalable production up to 200 L, aseptic fill‑finish, and full quality‑control testing. Multiple quality grades—such as research‑grade, GMP‑like, and GMP‑compliant—allow teams to tailor pDNA output to regulatory requirements. These services support both small‑scale milligram quantities and larger gram‑scale batches, with bioreactor capacities from 1 L to 200 L enabling seamless scale‑up. Off‑the‑shelf plasmids, including lentiviral, AAV, and molecular size marker constructs, provide rapid access when speed is critical. Processes are optimized to handle large plasmids up to 20 kb, ensuring efficiency across diverse applications. Overall, this adaptable platform delivers reliable pDNA supply, streamlined production, and the flexibility needed to align with evolving scientific and clinical goals.