Paveway™ PLUS Microbial Expression System For The Efficient Production Of Therapeutic Proteins

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The efficient expression of therapeutic proteins in microbial or mammalian systems is one of the major bottlenecks in the production of biopharmaceuticals.

Paveway™ is an innovative expression system in Escherichia coli (E. coli) that enables the creation of novel recombinant strains where the lead strain selection is based on titer possible within 6 weeks of program initiation. Since its launch in 2007, Paveway has become a well proven E. coli expression system, producing >140 different therapeutic proteins successfully expressed with a variety of accumulation routes including intracellular soluble, intracellular insoluble and periplasmic secretion.

In this article, review how the system works and a success story of the system in action.

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