PAT In Biologics - Strategies For Implementing PAT To Downstream Processing

Successful PAT programs are defined by a careful combined application of statistical process control (chemometrics) and use of on-ling, at-line, or near-line sensors and instrumentation capable of measuring key parameters of the manufacturing system in real time. These capabilities are arguably most critical and useful in the final stages of biotechnology manufacturing, where the value of the product is at its highest.

SOURCE: Groton Biosystems