Poster

Optimized Transient Production: Faster Preclinical Studies With Enhanced Quality Control

Source: Curia
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Optimizing transient protein production is essential for accelerating the development of biotherapeutics. High-quality plasmid DNA serves as a foundational element, significantly improving transfection efficiency and ensuring reliable expression. Complementing this, carefully optimized expression systems are key to maximizing protein titers while preserving the integrity and consistency of the final product.

Early-stage developability assessments further strengthen the process by evaluating critical biophysical properties — such as stability, solubility, and aggregation potential — to identify high-risk candidates before costly downstream development. Together, these integrated strategies compress preclinical timelines, provide faster access to functional proteins for informed decision-making, and enable a more seamless transition from discovery to clinical development — all without compromising quality, reproducibility, or regulatory readiness.

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