Brochure | February 15, 2023

Optimize Antibody Developability With Multi-Parameter Stability Data

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Prometheus instruments provide the highest quality data on multiple biophysical attributes of your antibody candidates. Collect information on thermal unfolding, particle sizing, and aggregation simultaneously, throughout the entire thermal ramp. 

Selecting the best antibody for development means sifting through data on hundreds, or even thousands, of candidates and conditions. Limited selection criteria or poor data quality make it difficult to choose just one candidate for advancement; but downstream assays on multiple candidates require time and investment on therapeutics that will never see the clinic.

See how one group at 2bind required both conformational and colloidal data — obtained from the same experiment — to optimize their buffer formulation. Get high-resolution, domain-specific stability characterization that unveils subtle differences between candidates, so you eliminate less stable options earlier in the pipeline. 

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