Newsletter | October 26, 2026

10.26.26 -- On The Ground At BPI: Jacqualyn Schulman, Ph.D., On Accelerating Clonal CLD

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The body as a bioreactor

What if therapeutic production could move from the facility into the patient? Explore how advances in lipid nanoparticle design, delivery science, and manufacturing are helping bring the body-as-a-bioreactor vision closer to reality—and reshaping what may be possible for genomic medicine.

FOCUS ON UPSTREAM MANUFACTURING

On The Ground At BPI: Jacqualyn Schulman, Ph.D., On Accelerating Clonal CLD

An interview with Jacqualyn Schulman, Ph.D., a principal scientist at Bristol Myers Squibb (BMS), on her presentation at BPI 2026, “Fast-Tracking CHO Cell Line Development Using Integrated Engineering Strategies.”

Achieving A 9-Month Timeline Through Integrated Cell Line Development

Uncover how tighter alignment between vector construction and cell banking improved development efficiency, strengthened risk management, and enhanced early-stage program outcomes.

Industrializing Cell Therapy With Perfusion

Explore how intensified perfusion strategies enable rapid, high‑density CAR‑T expansion, predictive scale‑down modeling, and efficient automated harvest, supporting shorter timelines and higher yields.

Modernizing Cell Banking: Scalable, Consistent, And Automated

Discover how automating cell banking workflows minimizes contamination risks and preserves viability in high-density cultures, ensuring consistent recovery and smoother scale-up.

Enhancing Laboratory Efficiency And Accelerating Time To Market

See how automated screening can accelerate CLD while preserving selection confidence, identifying promising candidates that manual methods may miss, and predicting poor fed-batch performers.

What Is A Viral Vector?

Review a novel adenovirus production process that offers scalable, single-use equipment-compatible solutions, reducing production time and cross-contamination risks.

How mAbs Have Transformed Breast Cancer Treatment, And Where It Is Going

Monoclonal antibody therapies are reshaping breast cancer treatment. Examine the latest manufacturing advances and research solutions helping developers accelerate therapy production at every stage.

CD8+ Single Positive T Cell Differentiation From HiPSC

Learn about a feeder-free method to differentiate CD8+ single positive T cells from human induced pluripotent stem cells, which offers promising advancements for scalable and efficient cell therapies.

Mammalian Or Microbial? Considerations When Choosing A System

Find out how whether you’re trying to achieve speed and cost-effectiveness or higher yields and glycosylation capabilities, the right system can be tailored to meet the needs of each unique biologic.

Enabling Commercial AAV Manufacturing By AAV Stable Producer Cell Lines

A high-performance, helper virus-free stable producer cell line is derived from proprietary high-producer HEK293 cells and is cultivated in a chemically defined, serum-free, ADCF medium in suspension.

Scaling In Vitro Glycoengineering From Lab To GMP

Access a phased, risk-minimized integration framework to scale your enzymatic post-production process seamlessly from initial lab-scale feasibility up to commercial GMP readiness.

UPSTREAM MANUFACTURING SOLUTIONS

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Used 200 Liter Sartorious Single Use Bioreactor, Model STR 200 DW - Federal Equipment Company

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Cell Culture Vessels: Closed Systems For High Yield Cell Growth - Corning Life Sciences

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Discover Our Collaborative Customer-Focused Approach - INFORS HT

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Webinar: Accelerating CHO Manufacturing: From 14-Day Fed-Batch to 10-Day Intensified Fed-batch

Webinar: Accelerating CHO Manufacturing: From 14-Day Fed-Batch to 10-Day Intensified Fed-batch 
 What if you could shorten a 14-day fed-batch process to just 10 days without sacrificing product quality? This Thermo Fisher Scientific webinar explores how N-1 perfusion intensified CHO-K1 Herceptin production using standard equipment and the same medium, while scaling from Ambr 250 to 50 L. Discover practical strategies to increase throughput, flexibility, and manufacturing capacity without significant process changes. Click here to learn more.

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Bio-Expo Live Nov 2026: Upstream Bioprocessing

Bio-Expo Live Upstream Manufacturing Session is a virtual event series for biopharma professionals focused on upstream manufacturing solutions. Attendees can explore new equipment and technologies for therapeutic areas like ADCs and vaccines through short, interactive presentations with live Q&A. The event is designed for biopharma companies and contract manufacturers seeking solutions to overcome drug development and upstream manufacturing challenges. Register now to reserve your spot!

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