Nuvia S Media

Nuvia™ S is an ultra high-capacity, next-generation cation exchange media built on the industry proven UNOsphere base matrix technology. Nuvia S provides very high capture and exceptional flow properties designed to meet current and future process needs. Nuvia S is a flexible alternative that may be used both as a capture or polishing solution. The media delivers superior binding capacity over a wide operational window, making it the tool of choice for a wide range of downstream processes.

Nuvia S delivers value and flexibility, by allowing users to:

• Use less media to purify a given amount of product
• Reduce cycle-time and increase productivity by operating at higher flow-rates
• Reduce costs and space requirements by decreasing buffer consumption
• Reduce capital and operating expenses through the use of smaller columns
• Chemical stability to withstand repetitive clean-in-place cycles
• Flexibility in use for capture or polish steps
• Fully supported for regulatory submission

Fig 1. Binding of polyclonal human IgG by Nuvia S media. Comparison of Nuvia S and other commercially available CEX media. Column size, 0.7 x 5.5 cm. The sample was loaded onto the column in 40 mM sodium acetate, pH 5.0 + 30 mM sodium chloride, washed, and then eluted with 40 mM sodium acetate, pH 5.0 + 1 M sodium chloride. DBC, Dynamic binding capacity. BT, breakthrough.

For a free sample visit: www.bio-rad.com/ad/doelicious