Novel Resin Functionalities Maximize Process Value For Biomolecule Purifications

With large scale production, biologics such as monoclonal antibodies (mAbs), recombinant proteins, viruses, and more recently, biosimilars and biobetters have become powerful therapeutics and have been shown to be effective in treating various human diseases. This book highlights several examples where creative use of chromatography resins and their unique functionalities has emerged as powerful tools and have produced tangible benefits such as higher process yield, reduced buffer consumption and processes with fewer unit operations. Several cases spanning a range of biomolecules and viruses are discussed with proven approaches to accelerate method development, thus allowing scientists to fine-tune selectivity and optimize downstream purification platforms.