Non Animal Origin Squalene Emprove® Expert: An Alternative Suitable For High-Risk Applications

Squalene is a naturally occurring lipid found in both shark liver oil and various plant-based oils. It plays a vital role in the development of modern vaccines through its use in nanoemulsion-based adjuvants. Adjuvants are ingredients added to vaccines to enhance the body’s immune response, which makes the vaccine more effective. In the case of squalene-based nanoemulsions, squalene is combined with surfactants to create a stable emulsion that acts as a powerful adjuvant. Several commercially available vaccine adjuvants—such as MF59, AS03, and AF03—contain squalene and have been successfully used in vaccines targeting seasonal and pandemic influenza viruses, as well as the SARS-CoV-2 virus responsible for COVID-19.

Understanding the role of squalene in vaccine development highlights the importance of continued research and innovation in immunology. If you're involved in healthcare, pharmaceuticals, or public health communication, now is the time to explore how squalene-based adjuvants can support your efforts in vaccine advancement.