New Paradigm For Bioprocessing Optimization And Control

Demands in bioprocessing and bioproduction continue to escalate due to cost pressure, competition, regulatory requirements, and new products. There is a critical need for new approaches, tools, technologies, and insights to support these demands. Metabolon has developed a novel, powerful paradigm for confronting these challenges.

Metabolon Experience in Bioprocessing
Hundreds+ client studies completed in bioprocessing/fermentation
• Pharma, Biotech and Bioindustrial
• All stages in the bioprocessing continuum: raw material profiling, clone strain/clone selection, process development, scale up and transfer, and batch fingerprinting
• CHO, NSO, stem cells, microbial and algae
• Peer-reviewed publications for cell culture optimization

Representative Outcomes
• Increased process yield
• Identified biomarkers for product quality and cell integrity
• Lactate production, disulfide bonds formation, complex raw material composition, disposable bioreactors, impact of trace metals, feed utilization, and more
• Characterized complex raw materials
• Successful root causes analyses at all development stages
• Optimized carbon flow for efficient biofuel production