Navigating Corning® HYPERStack® Cell Culture Vessels: A Collection Of Application Notes

To meet the rising global demand for advanced cellular therapies and viral vector production, scaling up adherent cell culture while maintaining high product quality is a critical bioprocessing priority. Traditional multi-layered vessels often face limitations in gas exchange and volumetric efficiency, which can compromise cell health and productivity at larger scales. High Yield PERformance (HYPER) technology addresses these challenges by utilizing an ultra-thin, gas-permeable film that significantly increases the growth surface area within a compact footprint.

Research across diverse applications—from expansion of human mesenchymal stem cells (MSCs) to adeno-associated virus (AAV) production and extracellular vesicle (EV) secretion—demonstrates how this platform supports robust yields and phenotypic consistency. Explore this collection of application notes to discover scalable strategies for optimizing your bioprocess.