NanoAssemblr™ Ignite And Ignite+ Nanoparticle Formulation Systems

NanoAssemblr™ Ignite+ | Total volume range 0.5 – 60 mL

Designed for process development, scale-up, and progression toward clinical manufacturing.

• Deliver reproducible results – Advanced NxGen™ mixing technology minimizes variability, delivers consistent nanoparticle performance across scales, and supports seamless transfer of formulation parameters as programs progress.
• Accelerate development timelines – Streamlined Ignite+ workflows support smooth scale-up across development stages. When your program is ready, use Ignite+ with the NxGen™ scale-ready cartridge 12 L/h to support small-scale clinical manufacturing.
• Scale with confidence – Model clinically relevant parameters at small volumes and scale up or scale down manufacturing processes while maintaining the same NxGen™ mixing technology, helping reduce process-development and technology-transfer risk.
• Choose how you use your cartridges – With a software upgrade, compatible NxGen™ cartridges can be reused, giving you the flexibility to choose the approach that best fits your budget, workflow, and quality needs.
• Reduced operational risk – Robust system design helps reduce user error, troubleshooting, and downtime. Single-use operation remains available when contamination control and operational simplicity are the priority.

NanoAssemblr™ Ignite | Total volume range 0.5 – 20 mL

Designed for research, early development, and reproducible bench-scale LNP formulation.

• Easy to use – Simple workflows and intuitive software allow users to quickly implement and operate the system with minimal training.
• Deliver reproducible results – Advanced NxGen™ mixing technology minimizes batch-to-batch and user variability to reproducibly generate homogeneous, high-quality nanoparticles.
• Choose how you use your cartridges – Reusable cartridge capabilities provide flexibility to tailor operations to your workflow and budget.
• Optimize efficiently – Quickly explore formulation parameters such as concentration, flow rate, and flow-rate ratio to identify promising candidates using small material volumes.

Ignite supports bench-scale total formulation volumes from 0.5 to 20 mL and flow rates up to 20 mL/min. Ignite+ supports total formulation volumes from 0.5 to 60 mL and flow rates up to 200 mL/min (12 L/h), supporting process development and progression toward small-scale clinical manufacturing with the NxGen™ scale-ready cartridge 12 L/h. Total volume refers to the amount of liquid formulated before dilution.

Scalable NxGen™ technology, flexible cartridge use

Shared NxGen™ mixing geometry across systems and scales supports the transfer of critical process parameters as programs progress, helping reduce scale-up and technology-transfer risk. Compatible NxGen cartridges can also be reused with a software upgrade, giving users the flexibility to select the cartridge-use approach that best fits their workflow, budget, and program needs. Single-use operation remains available when contamination control and operational simplicity are the priority.

Why work with Cytiva

Choose the technology, cartridge-use approach, and level of support that fit your program today. From research and formulation development through process development, technology transfer, and commercial manufacturing, Cytiva helps you scale with confidence on a globally trusted platform.

Commercially validated and globally trusted, the NanoAssemblr™ platform supports 2,000+ users, 1,500+ installed systems, 600+ scientific publication references, 20+ clinical programs, operations in 50+ countries, and one commercial program.