Brochure | March 26, 2021

Multi-Method Analysis - Detect Your Host Cell Protein Impurities

A well-developed ELISA method using Cygnus Technologies’ proprietary methods for antigen selection and antibody generation and purification, will be the linchpin method for host cell protein analysis. In addition to developing generic and process-specific ELISA kits, Cygnus Technologies is now pleased to offer sensitive and specific orthogonal methods to identify individual host cell protein impurities that persist through your purification process. These orthogonal methods include Mass Spectrometry, 2D PAGE, HPLC, and our proprietary AAE method, which is far superior to two-dimensional western blot. The integration of data from these orthogonal methods together with ELISA data provide a comprehensive analysis of HCP content, that will meet regulatory expectations.

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