Mobius® ADC Reactor

The Mobius® ADC Reactor is a family of single-use mixing systems tailored for the conjugation step in the production of Antibody Drug Conjugates (ADCs). With scalability options ranging from 4 L to 500 L, this solution brings the advantages of single-use systems to conjugation. These benefits include faster turnaround times, no risk of cross-contamination, and the elimination of cleaning and validation steps—all while ensuring process continuity, high product quality, and the safety of operators.

Building on the proven designs of the Mobius® MIX and Power MIX single-use mixers, the Mobius® ADC Reactor addresses the unique challenges of the conjugation step. Its single-use assemblies are constructed from Ultimus® Film technology, offering improved bag strength, durability, and leak resistance for enhanced safety. The integration of woven nylon in the new film boosts durability while maintaining the flexibility, ease of handling, and compliance needed for ADC processes. Read on to explore the advantages of applying single-use to conjugation and gain insight into the performance of the reactor.