Newsletter | February 27, 2024

02.27.24 -- Maximize Adherent Cell Yields With Perfusion

Is A Perfusion Cell Culture System Right For Adherent Cultures?

How do you know when to make the switch to a perfusion setup? Read through advice from industry experts on popular perfusion applications, what makes a perfusion system better than static modalities for adherent cultures, and more helpful insights.

 

Expansion Of DF-1 Cell Line In A Circulation/Perfusion System

This study establishes basic cell culture parameters for the expansion of DF-1 cells in the Corning CellCube System for avian vaccine production applications. This system offers a compact and scalable method for the mass culture of attachment-dependent cells.

 

Evaluating The Corning CellCube System

Explore a “plug-and-play” setup for cell expansion in a CellCube circulation/perfusion system using a spinner flask as a substitute for a bioreactor controller. This study also compared cell growth characteristics in the CellCube incubator setup to a traditional bioreactor-controlled CellCube system and found them to be comparable.

 

Serum-Free Culture Of Vero Cells In The Corning CellCube System

The Vero cell line is widely used for both viral vector and vaccine production. Explore a framework for optimizing the process and developing protocols for expanding Vero cells in serum-free medium at a small scale, which can be scaled up for production in larger CellCube systems.

 

SOLUTIONS

Corning CellCube System

The Corning CellCube system provides a compact, perfusion-based method for the mass culture of attachment-dependent cells. CellCube modules consist of a series of 10, 25, or 100 parallel, polystyrene plates joined to create thin, sealed laminar flow spaces between adjacent plates.

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Frequently Asked Questions: Corning CellCube System

Corning scientists’ answers to FAQs on CellCube system specifications, protocols, and applications may help you determine if this perfusion-based system is right for you.

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