Mammalian Services: Protein Manufacturing

Mammalian‑based manufacturing platforms provide a comprehensive path from early development through large‑scale clinical production, supporting biologics that require human‑like glycosylation, high productivity, or specialized expression systems. These services typically include clone generation, cell line development, process optimization, scale‑up, analytical transfer, formulation, and GMP manufacturing runs. Available expression systems often span CHO, HEK, and other host lines, using either licensed or freedom‑to‑operate options to suit project needs. Facilities equipped for both non‑GMP and GMP production allow seamless progression from small‑scale engineering runs to larger volumes, with bioreactor capacities ranging from 50 L to 2,000 L. Downstream processing capabilities include chromatography, filtration, and single‑use technologies for compliant purification workflows.

Timelines for delivering GMP material can be accelerated through integrated development and manufacturing frameworks. Overall, mammalian services provide the flexibility, scalability, and technical depth required to efficiently advance biologics toward clinical supply.