3M™ Emphaze™ AEX Hybrid Purifier: Biopharmaceutical Innovation - Pure And Simple
Biopharmaceutical purification is a complex process, composed of multiple unit operations. The 3M™ Emphaze™ AEX Hybrid Purifier is designed to simplify biopharmaceutical manufacturing, including that of recombinant proteins and monoclonal antibodies (mAb), by providing flowthrough chromatographic separation of contaminants.
Emphaze AEX Hybrid Purifier delivers consistent, high-purity clarified process fluid by reducing cell debris, DNA, HCP and endotoxin, through a combination of chromatographic and size-exclusion mechanisms. This provides a more efficient process from end to end: product recovery can be substantially increased by reducing the sterilizing membrane surface area pre-Protein A, eliminating the post-viral inactivation depth filter clarification requirement and combining polishing trains into one connected operation.
Integrating Emphaze AEX Hybrid Purifier in the clarification stage may reduce the total cost of ownership for the mAb purification process. Single-use designs reduce time and cost for cleaning validation.
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