Newsletter | October 27, 2025

10.27.25 -- Looking to outsource pDNA or mRNA process development?

5 Key Considerations For Companies Outsourcing Process Development

Biotech investment remains strong, especially in cell and gene therapies. Learn five key factors that help companies decide between in-house and outsourced process development to improve speed, scalability, and strategic alignment.

 

Best Practices For A Successful Bioprocess Technology Transfer

Effective bioprocess tech transfer ensures consistent performance and minimizes risk across sites. Discover how strategic planning and knowledge sharing can safeguard reproducibility and product quality during scale-up or site transitions.

 

A Risk-Based Approach To Plasmid DNA And mRNA Process Development

Balancing analytical depth with clinical speed is critical for early-phase pDNA and mRNA therapies. Find out how teams can navigate structural complexity and regulatory demands without compromising development timelines or therapeutic integrity.

 

Optimization And Scale-Up Of A Plasmid DNA Production Process

Plasmid DNA production in E. coli is a cornerstone of gene therapy and vaccine development. Explore how media selection and scale-up strategy influence plasmid DNA yield in E. coli, as well as which conditions support high-yield production and how to apply them to your upstream process for better consistency.

 

Scale Up Your E. Coli pDNA Process From Parameter Screening To Pilot Scale

Examine how DOE-driven optimization with E. coli OneShot Top10 enables scalable, high-yield plasmid DNA production, as well as gain practical insights into upstream process design for improved efficiency, consistency, and biomanufacturing success.

 

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