Lentiviral Vector Characterization Made Easy With Maurice CE-SDS

Several factors are involved in a smoother, accelerated viral vector-based gene therapy pipeline, including the adoption of robust analytical tools across various stages. The accurate characterization of viral vectors for various attributes such as purity, identity, viral titer, and safety is critical. Even today, LVVs are characterized for some of their attributes with techniques such as SDS-PAGE and ELISA. SDS-PAGE is a manual and laborious method that often comes with reproducibility issues, while ELISAs can overestimate the viral titer present. To address the challenges presented by these analytical techniques, this application note demonstrates a robust and automated CE-SDS method.