Laboratory Microchip

The LabChip uses semiconductor-like microfabrication techniques to build various chip architectures, such as interconnected fluid reservoirs and pathways. Using this technology, all sample preparation, fluid handling, and biochemical analysis steps can be carried out within the confines of a microchip. Fluid transport is effected by strategically located electrodes that create electrokinetic forces capable of driving fluids through selected pathways just as fluids are driven by the voltage gradient applied between electrodes in capillary electrophoresis. Proper balancing and/or sequencing of voltage inputs controls the speed and direction of fluid movement. This chip, when used in concert with experimental protocols developed in software, is said to comprise the heart of a nanoscale laboratory.

Hewlett-Packard Co., Chemical Analysis Div., 2850 Centerville Rd., Wilmington, DE 19808 Phone: (302) 633-8696 Fax: (302) 633-8993