ÄKTA ready™ Chromatography System 450

ÄKTA ready™ chromatography system 450 is a single-use liquid chromatography system designed for small-scale manufacturing. To meet the needs of purifying small drug volumes, the system has a low flow range of 5 to 450 mL/min per pump and a low hold-up volume. The single-use flow path minimizes the need for cleaning and cleaning validation, allowing for quick changeover between productions and reducing the risk of carryover.

The system offers the performance and documentation required for use in a GMP-regulated environment.

Designed for small-scale manufacturing:

• Small hold-up volume and flow rate support efficient purification of small drug volumes.
• Gamma-irradiated single-use closed flow path reduces contamination risk and cleaning validation efforts. Option for aseptic connectors.
• Multi-wavelength UV detection and low shear pump support purification of viral vectors and other sensitive biomolecules.
• Small benchtop footprint makes efficient use of valuable facility space.

Learn about system specifications, manufacturing capabilities, and much more.