Innovate And Accelerate: Leveraging 3Rs For Superior Cell Line Characterization

Biologics safety testing is changing as regulators increasingly recognize non-animal methods that support the 3Rs: replacement, reduction, and refinement of animal testing. Advances such as next generation sequencing (NGS) are helping reshape long-standing approaches to adventitious virus detection, offering a path toward faster, more comprehensive safety assessments without relying solely on traditional in vivo methods. Learn how the regulatory landscape is evolving, what it takes to build a practical 3Rs roadmap, and how newly published data supports the use of NGS as a replacement for in vivo adventitious virus testing. See how modern technologies can be integrated into a streamlined cell line characterization package to help accelerate development while maintaining confidence in biologics safety.