Application Note

Improving CD Media Titers With Nu-Tek Peptones

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Transitioning to chemically defined media (CDM) allows for maximum process control, but supplementing these formulations with animal-free complex materials can significantly augment culture outputs. Research indicates that adding 0.2% soy peptone to different commercially available CDM formulations increases IgG production by 30% to 60%. This approach offers several key advantages for biopharmaceutical production:

  • Increased Efficiency: Higher IgG yields are consistently achieved across multiple media formulations.
  • Streamlined Operations: Manufacturing is simplified by reducing the overall complexity of the media formulation.
  • Risk Mitigation: Utilizing a 100% animal-free primary or secondary nutrient source helps navigate quality and regulatory risks.

By integrating these peptones and yeast extracts, facilities can maximize productivity and fuel cell growth through a secure, high-value nutritional portfolio.

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