06.06.25 -- How Modeling Predicts Bottlenecks In Takeda's Multimodal Facilities

Micromirror TIRF microscopy is a groundbreaking advancement that offers unprecedented clarity, revolutionizing our understanding of molecular assembly and cellular processes, and propelling biological research forward.

Combining Functional Design of Experiments (Functional DOE) with traditional DOE methods enhances biopharmaceutical process optimization by capturing dynamic, time-based variations in cell culture systems.

Through a carefully executed strategy, see how we identified novel degrader molecules with the right physicochemical properties to achieve robust degradation of the target Protein of Interest (POI).

Join Dr. Ladbury to explore how thermodynamic data can enhance our understanding of protein-ligand interactions and how it is crucial for optimizing drug efficacy and safety in pharmaceutical development.

Adopt QbD principles in your biologics development and manufacturing process to ensure consistent product quality, mitigate risks, and align with patient safety and commercial success goals.

Gain insights that can support your next steps, whether advancing to a new clinical phase, constructing a new facility, or fine-tuning an existing process to keep pace with market shifts.

Learn about a program that has been developed to facilitate risk mitigation before process-specific filter validation is performed.

A company needed to produce the registration batches of a generic broad-spectrum antibiotic. Learn how a CDMO with an experienced project management team helped meet the unprecedented 4-month timeline.

Delve into the specific challenges encountered in the development of high-concentration formulations and gain an overview of current state-of-the-art solutions for subcutaneous administration.

Jin Lu, Ph.D., Senior Technical Support Manager, shares how novel expression tools can advance your early-stage bispecific antibody discovery programs toward clinical success.

If you’re hoping to improve your QC toolkit to better accommodate complex modalities like cell and gene therapies, it's time to build a program that accounts for risk and unique product characteristics.

Technological advances have made it possible to produce high-quality T cells at scale, providing a boon for T-cell manufacturing.

This article collection highlights the importance of continued research and development in the field of bioprocessing to revolutionize the next generation of therapies and personalized medicine.

Learn the principles of commercialization readiness and guidance to address them in process development as well as the best time to implement automation and minimize commercialization risks.

See why single-use cold-chain containers made with polytetrafluoroethylene fluoropolymers may be less susceptible to failure and breakage at cold temperatures.

Explore ways to tackle the process step of freezing and thawing when it comes to manufacturing quality biopharmaceutical products, like ADCs, at scale.

To safeguard the consistent delivery of essential therapies to patients around the world, biopharmaceutical companies, alongside their CDMO partners, are rethinking traditional supply models.