How Does CHT™ Ceramic Hydroxyapatite Media Work?

CHT Ceramic Hydroxyapatite is a mixed-mode chromatography media used for the purification of monoclonal and polyclonal antibodies, antibody fragments, enzymes, nucleic acids, and membrane proteins. It is formed from the chemical combination of calcium and phosphate sales. Biomolecules can interact with CHT through calcium affinity interactions and/or cation exchange interactions. This PDF highlights the different ways in which these chemical interactions can occur.