Greg Sacha, Ph.D., Global Senior Scientist, Development & Pre-Commercial Services

Drug products that are unstable as liquids can be frozen or freeze-dried (lyophilized). While frozen products require specialized transportation and storage facilities, a room-temperature or refrigerated lyophilized product is significantly easier to store, as well as distribute, and has a longer shelf life. In this article, Greg Sacha, Global Senior Scientist, Development and Pre-Commercial Services, highlights the advantages and challenges of product lyophilization, the development of lyophilization processes on site at Simtra BioPharma Solutions’ Bloomington, Indiana, plant and the importance of continuing research.