Formulating The Future: A Practical Guide To Nucleic Acid Therapeutics

Nucleic acid–based therapeutics are rapidly transforming modern medicine, but their development comes with unique scientific and formulation challenges. This webinar provides a comprehensive overview of the nucleic acid therapeutic landscape, spanning mRNA, DNA, antisense oligonucleotides, siRNA, aptamers, CRISPR-Cas systems, and vaccine adjuvants. Beginning with foundational mechanisms of action, the session explains how these diverse modalities function and where they are currently applied clinically.

The discussion then shifts from theory to practice, highlighting key considerations in drug product development such as delivery system selection, stability, sterilization strategies, and formulation optimization. Through detailed case studies, attendees gain insight into real-world decision-making around terminal sterilization, lipid nanoparticle size and payload optimization, scalability, and lyophilization feasibility.

Designed for scientists, developers, and decision-makers, this webinar emphasizes the importance of early formulation strategy, data-driven development, and an integrated analytical approach to accelerate successful nucleic acid therapeutic programs.