Newsletter | September 2, 2026

09.02.26 -- Fixing AAV Recovery With Siren Biotechnology's Nathalie Clément, Ph.D.

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Webinar: Driving Productivity Across the Antibody Manufacturing Workflow

Rising antibody titers create challenges for harvest, purification, scalability, and cost. Join Thermo Fisher Scientific experts to explore integrated upstream and downstream strategies for improving therapeutic antibody manufacturing. Discover practical approaches to harvest clarification, Protein A capture, polishing, and purification optimization, plus case study data demonstrating scalable performance and economic impact. Learn how integrated solutions can simplify scale-up and improve productivity. Click here to learn more.

FOCUS ON FILL-FINISH

 

5 Ways Pre-Filled Syringes Contribute To Better Patient Outcomes

In our series on pre-filled syringes, we explore five key ways this delivery format is enhancing patient outcomes, not just through the medicine it contains, but through the device design itself.

 

End-To-End Custom Media From The Right Formulation To GMP

Uncover how integrated custom media solutions can accelerate the path to manufacturing success, supporting both clients with established formulations and those seeking new designs.

FILL-FINISH SOLUTIONS

Automated Robotic Fill-Finish: Available With Accelerated Delivery - AST

FOCUS ON DOWNSTREAM MANUFACTURING

Fixing AAV Recovery With Siren Biotechnology's Nathalie Clément, Ph.D.

In this episode of “Better Biopharma,” host Tyler Menichiello is joined by Nathalie Clément, Ph.D., Siren Biotechnology’s SVP of vector development. The two discuss the historical challenges of purifying AAV vectors and the developments that have allowed for greater product yields.

 

 

What Is Size Exclusion Chromatography (SEC)?

Aggregation can compromise mAb quality at many stages. Learn why size exclusion chromatography is a trusted approach for detecting aggregates and supporting confident characterization.

 

Single-Use Virus Filtration: Controllers And Systems

Modern single-use virus filtration automates critical processing steps, slashes turnaround times, and optimizes scalability across bioprocessing workflows.

 

Four Common Pitfalls To Avoid In UF/DF Setup And Scale-Up

See how small UF/DF decisions can create major scale-up challenges, as well as practical ways to improve membrane selection, reduce manual operations, and boost PD–MSAT alignment.

 

Wetting Recommendations For Successful Filter Integrity Testing

Discover best practices for hydrophobic and hydrophilic filters, troubleshoot failures, and optimize wetting in stainless steel and single-use systems to ensure process reliability and product quality.

 

The Evolving Landscape Of Fill/Finish: Trends, Challenges, What's Ahead

Examine how surging demand for GLP-1 and other therapeutics is transforming fill/finish capacity and regulatory standards. Learn how CDMOs are adapting to the complex needs of emerging modalities.

DOWNSTREAM MANUFACTURING SOLUTIONS

Single-Use Solutions For Critical Fluid Management Workflows - Charter Medical

Scale Up: Supporting Easy Scalability All The Way To Manufacturing - Cytiva

Bioconjugation Services: Link Your Antibody To Its Fullest Potential - Samsung Biologics

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