FATHOM: A New Type Of EPR Spectrometer

Characterizing dynamic and intrinsically disordered proteins presents a significant challenge in structural biology, particularly when researching disease targets like Alzheimer's, Parkinson's, and ALS. While established techniques such as cryo-EM and NMR yield valuable structural data, capturing conformational flexibility often requires complementary analytical approaches. Superconducting quantum sensors in electron paramagnetic resonance spectroscopy achieve exceptional sensitivity while requiring minimal sample volumes. Combining high-sensitivity detection with automated operation broadens access to advanced biophysical measurements across research teams. When integrated alongside standard structural tools, quantum-enabled spectroscopy offers critical insights into complex macromolecular behavior, helping biopharmaceutical and academic laboratories resolve challenging protein structures and accelerate target validation. Explore how quantum sensing technology can enhance your structural biology workflow.