Exosomes

Exosomes are nano-sized vesicles that enable unique intercellular communication by transferring DNAs, microRNAs, non-coding RNAs, and lipids.
Exosomes have been identified as having potential applications in diagnostics and therapeutics for various diseases.
Serving as vesicular carriers, exosomes can facilitate communication between cells, making them a central focus in therapeutic applications, encompassing cargo properties, targeting functions, and diverse tissue-specific sources.
Our Capabilities:
- Exosome production from various tissue types of MSCs using 2D/3D culture systems.
- Leverage scalable 3D microcarrier technology for high-efficient upstream production.
- A downstream process for exosome purification through ultracentrifugation has been established; the scalable downstream processes using TFF and chromatography are under development.
The Flowchart for Exosome Production from MSCs Using 3D Microcarrier-Based Process:
This flowchart outlines how Mycenax utilizes the 3D microcarrier-based process for the cultivation of mesenchymal stem cells (MSCs) and the purification of exosomes from the harvested supernatant, thereby producing the final exosome drug product.
Leveraging Microcarrier-Based Process, Roosterbio’s Products and Ambr250 Mini-Bioreactor System to Increase Exosome Productivity
- High Cell Density and Persistent Productivity During Exosome Collection Phase
- Scalable Upstream Process