Everything You Ever Wanted To Know About Cell Culture Process Transfer

By Kulwant Kandra

A specific product is usually produced by thawing the cells, cultivating these up to a certain amount of cell density in incubated shakers, followed by then transferring the process into a bioreactor. To increase the amount of product, the bioprocess is accordingly finally scaled-up to different unit sizes. However, the steps taken to make this switch are easier said than done. Explore how to make the transfer successful with through topics such as choosing the right impeller design, critical engineering parameters and the "scaling-up recipe".