Enzymatic Peptide Synthesis

Enzymatic Peptide Synthesis is designed to make peptides and small proteins of biological and pharmaceutical interest. In order to make full use of enzymatic alternatives, a universally applicable peptide ligase is needed which would display high catalytic efficiency for all possible combinations of amino acids to be coupled. The ideal tool is an absolutely nonspecific peptide ligase as represented by the ribosomal peptidyl transferase.

Included among the peptide and peptidomimetic synthesis reagents are resins for SPPS, Boc-amino acids and building blocks, Fmoc-amino acids and building blocks, and Z-amino acids and building blocks. Additionally, the line includes B-amino acids, N-methyl amino acids, coupling reagents and additives, linkers, monitoring reagents, solvents, deprotecting reagents, protecting group reagents, miscellaneous reagents, and enzymatic PS.

Sigma Aldrich, 1001 W. Saint Paul Ave., Milwaukee, WI 53233. Tel: 414-273-3850; Fax: 414-273-4979.