Enrichment Of Human CD4+ And CD8+ Antigen-Specific T Cells: Cytokine Capture System (IFN-Gamma)

Rapid access to antigen-specific T cells is critical for advancing personalized immunotherapy and cell manufacturing workflows. The Cytokine Capture System (IFN-gamma) enables fully automated enrichment of IFN-γ-secreting CD4+ and CD8+ T cells following antigen-specific stimulation, supporting the isolation of virus- and cancer antigen–reactive immune cells. Designed for use with a broad range of peptide pools, the workflow integrates cell processing, labeling, and magnetic enrichment into a streamlined process on a single platform.

The application note highlights key workflow steps, material requirements, process specifications, and system setup considerations, offering a practical guide for laboratories seeking reproducible enrichment of antigen-specific T cells. Explore how automation helps standardize processing while reducing hands-on time and supporting consistent product quality.