Enhanced Paveway™ PLUS Selects Expression Organisms Based On Titer Plus Quality

Launched in 2007, our core microbial expression system Paveway™ has offered industry leading titers by enabling lead strain selection based on product titer in six weeks from program initiation, that has resulted in the successful expression of 150+ proteins.

Our enhanced Paveway™ PLUS platform operates through an enhanced workflow providing exceptional product titers for a wide range of soluble and insoluble proteins, while maintaining extremely tight control of pre-induction product expression. Fermentations can be run without antibiotic selection pressure while sustaining high plasmid retention, helping avoid regulatory concerns around potential antibiotic resistance and clearance.

This case study highlights the ability of the Paveway PLUS enhanced workflow to detect post translational modifications in partially purified product.