Dynal Biotech Inc.
Source: Dynal Biotech Inc.
Dynal - From Discovery to Bioseparation Standard
In 1979, Professor John Ugelstad of Norway achieved something under normal gravity otherwise only achieved by NASA in the weightless conditions of space - the making of uniform polystyrene spheres of exactly the same size. Prof. Ugelstad and his colleagues made these spheres magnetisable and, moreover, superparamagnetic meaning they are only magnetic in a magnetic field. Due to this property, the particles can easily be resuspended when the magnetic field is removed. This discovery has revolutionised the isolation and separation of many biological materials. For instance, the attachment of target-specific antibodies to the surface of the beads allows capture and isolation of intact cells directly from a complex suspension, such as blood. This is all accomplished under the influence of a simple magnetic field without the need of column techniques or centrifugation.
In 1979, Professor John Ugelstad of Norway achieved something under normal gravity otherwise only achieved by NASA in the weightless conditions of space - the making of uniform polystyrene spheres of exactly the same size. Prof. Ugelstad and his colleagues made these spheres magnetisable and, moreover, superparamagnetic meaning they are only magnetic in a magnetic field. Due to this property, the particles can easily be resuspended when the magnetic field is removed. This discovery has revolutionised the isolation and separation of many biological materials. For instance, the attachment of target-specific antibodies to the surface of the beads allows capture and isolation of intact cells directly from a complex suspension, such as blood. This is all accomplished under the influence of a simple magnetic field without the need of column techniques or centrifugation.
From this discovery and to ensure its development, a joint venture company - Dynal, headquartered in Oslo, Norway - was formed in 1986 between Dyno Industrier ASA and A.L. Industrier AS, combining knowledge from the chemical, pharmaceutical and biotechnological fields.
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