10.21.24 -- Discovery Vs. Hypothesis-Driven Cell Line Development

Traditional depth filtration struggles with lentiviral harvest clarification, leading to low yields and high costs. However, single-use centrifugation offers a promising alternative.

Discover how Organ-on-a-Chip technology revolutionizes drug development, overcoming the limitations of traditional models to create more accurate, efficient pathways to life-saving treatments.

Gain insights into the latest advancements in high-resolution multi-plane whole well imaging and the impact of AI-powered image analysis on clonality decisions and optimal clone selection.

Explores various strategies to enhance viral titer and increase the percentage of full AAV capsids, like modifications to transfection reagents, cell lines, media, procedures, and more.

Review key methods which are applied to ensure safety of such recombinant proteins, with a focus on alternate and superior methods to the standard transmission electron microscopy (TEM) method.

This study describes a “plug-and-play” setup for cell expansion in Corning CellCube 25-layer modules in the absence of a bioreactor controller.

These single-use bioreactors can make life in the lab easier with an easy setup, workflow, and 3D printing technology that allows you to customize the bioreactor to your application.

Gain valuable insight into the optimization and scalability of perfusion media and processes, driving progress in biotechnological processes for monoclonal antibody production.

CD34+ cells isolated from cord blood were expanded in a hollow-fiber bioreactor using a novel cytokine cocktail at one-tenth the standard concentration using a MSC-free coating strategy.

Low AAV productivity and lack of platform processes continue to be key challenges driving AAV production cost up. Explore a robust and scalable suspension manufacturing platform for AAV production.