Develop A Performance Model Optimized For Yield And Quality Of The mRNA Product

Optimize your mRNA production by identifying an optimum set of conditions for the in vitro transcription (IVT) reaction that produces high-quality mRNA in high yield using a design of experiment (DoE) approach. Previous optimization data has demonstrated that factors such as magnesium and nucleotide concentrations significantly impact the yield performance of IVT reactions Other studies show that the interaction between optimal amounts of these components is essential to produce high yields, especially with special construct designs like self-amplifying RNA (saRNA). Through this DoE study we discover how GMP-grade, fit-for-purpose mRNA raw materials can enhance your mRNA technology platform.