Characterization Of Antibody-Drug Conjugate Critical Quality Attributes Using The Agilent Cary 3500 UV-Vis Multizone Temperature Capability

By Aveline Neo and Suresh Babu C.V

Understanding and controlling critical quality attributes is essential as antibody-drug conjugates (ADCs) move through development and manufacturing. Reliable measurement of drug-to-antibody ratio (DAR) and aggregation provides insight into product consistency, stability, and performance. Advanced UV-Vis technology enables simultaneous, multi-temperature analysis, bringing greater efficiency and confidence to characterization workflows. With straightforward methods, built-in calculation capabilities, and precise temperature control, it becomes easier to generate consistent, reproducible data without added complexity. For teams working to streamline analytical processes while maintaining rigorous quality standards, this approach offers a practical path to more informed decision-making.

Observe how enhanced UV-Vis capabilities can simplify ADC analysis and support robust bioprocessing outcomes.