CE-SDS Analysis Of A NISTmAb Reference Standard Using Both Maurice And The SCIEX PA 800/PA 800 Plus

Regulatory agencies require that all biopharmaceutical companies monitor critical quality attributes for any monoclonal antibody therapeutic product. CE-SDS is a commonly used method as it provides purity and identity information required by the FDA.

Maurice and Maurice S. systems totally transform conventional CE-SDS separation and analysis, streamlining the entire process.¹ Maurice S. runs CE-SDS applications, and Maurice lets you analyze samples two ways using either CE-SDS or cIEF. There’s no optic calibration needed, and all steps of the assay happen in a ready to go CE-SDS cartridge. Maurice automates everything too, so potential sources of error are minimized. That means you’ll get really high quality data all the time. Clean-up between batches takes less than six minutes, with absolutely no cross-contamination between batches.

In this application note, we’ll show you how Maurice data compares against SCIEX PA 800 systems for reduced and non-reduced CE-SDS separation of a reference monoclonal antibody from the National Institute of Standards and Technology (NIST).

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